Llwytho...
1,4-Dideoxy-1,4-imino-d-lyxitols and L-lyxitols may bind to Golgi α-mannosidase II in a different protonation form
Development of effective inhibitors of Golgi α-manosidase II (GMII, E.C.3.2.1.114) with minimal off-target effect toward lysosomal α-manosidase (LMan, E.C.3.2.1.24) is a complex task due to complicated structural and chemical nature of their active sites. The pK(a) values (and also protonation forms...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Org Biomol Chem |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2022
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614232/ https://ncbi.nlm.nih.gov/pubmed/36322142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d2ob01545e |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|