Llwytho...

‘Click chemistry‘ synthesis of 1-(α-d-mannopyranosyl)-1,2,3-triazoles for inhibition of α-mannosidases

Three new triazole conjugates derived from D-mannose were synthesized and assayed in in vitro assays to investigate their ability to inhibit α-mannosidase enzymes from the glycoside hydrolase (GH) families 38 and 47. The triazole conjugates were more selective for a GH47 α-mannosidase (Aspergillus s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Carbohydr Res
Prif Awduron: Poláková, Monika, Stanton, Rhiannon, Wilson, Iain B. H., Holková, Ivana, Šesták, Sergej, Machová, Eva, Jandová, Zuzana, Kóňa, Juraj
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382718/
https://ncbi.nlm.nih.gov/pubmed/25658064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2015.01.004
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