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Refactored genetic codes enable bidirectional genetic isolation

The near-universal genetic code defines the correspondence between codons in genes and amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli and created orthogonal genetic codes that restrict the escape of synthetic genetic information into natural life. We dev...

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Publicat a:Science
Autors principals: Zürcher, Jérôme F., Robertson, Wesley E., Kappes, Tomás, Petris, Gianluca, Elliott, Thomas S., Salmond, George P. C., Chin, Jason W.
Format: Artigo
Idioma:Inglês
Publicat: 2022
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614150/
https://ncbi.nlm.nih.gov/pubmed/36264827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.add8943
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