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Refactoring the Genetic Code for Increased Evolvability

The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid. Saturation mutagenesis experiments suggest that in some cases the best-performing mutant requires repl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:mBio
Prif Awduron: Pines, Gur, Winkler, James D., Pines, Assaf, Gill, Ryan T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686537/
https://ncbi.nlm.nih.gov/pubmed/29138304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01654-17
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