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Refactoring the Genetic Code for Increased Evolvability
The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid. Saturation mutagenesis experiments suggest that in some cases the best-performing mutant requires repl...
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| Udgivet i: | mBio |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686537/ https://ncbi.nlm.nih.gov/pubmed/29138304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01654-17 |
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