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Refactoring the Genetic Code for Increased Evolvability

The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid. Saturation mutagenesis experiments suggest that in some cases the best-performing mutant requires repl...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Pines, Gur, Winkler, James D., Pines, Assaf, Gill, Ryan T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686537/
https://ncbi.nlm.nih.gov/pubmed/29138304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01654-17
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