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Refactored genetic codes enable bidirectional genetic isolation
The near-universal genetic code defines the correspondence between codons in genes and amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli and created orthogonal genetic codes that restrict the escape of synthetic genetic information into natural life. We dev...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614150/ https://ncbi.nlm.nih.gov/pubmed/36264827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.add8943 |
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