Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

Ferroptosis is a type of cell death caused by radical-driven lipid peroxidation, leading to membrane damage and rupture. Here we show that enzymatically produced sulfane sulfur (S(0)) species, specifically hydropersulfides, scavenge endogenously generated free radicals and, thereby, suppress lipid p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Barayeu, Uladzimir, Schilling, Danny, Eid, Mohammad, Xavier da Silva, Thamara Nishida, Schlicker, Lisa, Mitreska, Nikolina, Zapp, Christopher, Gräter, Frauke, Miller, Aubry K., Kappl, Reinhard, Schulze, Almut, Friedmann Angeli, José Pedro, Dick, Tobias P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2022
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613997/
https://ncbi.nlm.nih.gov/pubmed/36109647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01145-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados