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Point estimation for adaptive trial designs I: A methodological review
Recent FDA guidance on adaptive clinical trial designs defines bias as “a systematic tendency for the estimate of treatment effect to deviate from its true value,” and states that it is desirable to obtain and report estimates of treatment effects that reduce or remove this bias. The conventional en...
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| Publicat a: | Stat Med |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Inc.
2022
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613995/ https://ncbi.nlm.nih.gov/pubmed/36451173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9605 |
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