Adaptive designs in clinical trials: why use them, and how to run and report them

Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are often more efficient, informative and ethical than trials with a traditional fixed design sin...

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Foilsithe in:BMC Med
Main Authors: Pallmann, Philip, Bedding, Alun W., Choodari-Oskooei, Babak, Dimairo, Munyaradzi, Flight, Laura, Hampson, Lisa V., Holmes, Jane, Mander, Adrian P., Odondi, Lang’o, Sydes, Matthew R., Villar, Sofía S., Wason, James M. S., Weir, Christopher J., Wheeler, Graham M., Yap, Christina, Jaki, Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Correspondence
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830330/
https://ncbi.nlm.nih.gov/pubmed/29490655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1017-7
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