Carregant...
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination
DNA interstrand crosslinks are tumor-inducing lesions that block DNA replication and transcription. When crosslinks are detected at stalled replication forks, ATR kinase phosphorylates FANCI, which stimulates monoubiquitination of the FANCD2-FANCI clamp by the Fanconi anemia (FA) core complex. Monou...
Guardat en:
| Publicat a: | Nat Struct Mol Biol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2022
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613635/ https://ncbi.nlm.nih.gov/pubmed/36050501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-022-00820-9 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|