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Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA

The Fanconi anaemia (FA) pathway is a dedicated pathway for the repair of DNA interstrand crosslinks and is additionally activated in response to other forms of replication stress. A key step in the FA pathway is the monoubiquitination of each of the two subunits (FANCI and FANCD2) of the ID2 comple...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Rennie, Martin L, Lemonidis, Kimon, Arkinson, Connor, Chaugule, Viduth K, Clarke, Mairi, Streetley, James, Spagnolo, Laura, Walden, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332966/
https://ncbi.nlm.nih.gov/pubmed/32510829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050133
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