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Allosteric mechanism for site-specific ubiquitination of FANCD2
DNA damage repair is implemented by proteins that are coordinated by specialised molecular signals. One such signal in the Fanconi Anemia (FA) DNA-interstrand crosslink repair pathway is the site-specific monoubiquitination of FANCD2 and FANCI. The signal is mediated by a multi-protein FA core compl...
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| Udgivet i: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035956/ https://ncbi.nlm.nih.gov/pubmed/31873223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0426-z |
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