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Potential disease modifying therapies for Huntington’s disease, lessons learned and future opportunities
Huntington’s disease is the most frequent autosomal dominant neurodegenerative disorder, for which we have no approved disease-modifying treatments. The molecular pathogenesis of Huntington’s disease is complex, with toxicity arising from full length expanded huntingtin and N-terminal fragments of h...
Shranjeno v:
| izdano v: | Lancet Neurol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2022
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613206/ https://ncbi.nlm.nih.gov/pubmed/35716694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(22)00121-1 |
| Oznake: |
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