Natural biological variation of white matter microstructure is accentuated in Huntington's disease

Huntington's disease (HD) is a monogenic neurodegenerative disorder caused by a CAG‐repeat expansion in the Huntingtin gene. Presence of this expansion signifies certainty of disease onset, but only partly explains age at which onset occurs. Genome‐wide association studies have shown that natur...

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Dettagli Bibliografici
Pubblicato in:Hum Brain Mapp
Autori principali: Gregory, Sarah, Crawford, Helen, Seunarine, Kiran, Leavitt, Blair, Durr, Alexandra, Roos, Raymund A. C., Scahill, Rachael I., Tabrizi, Sarah J., Rees, Geraint, Langbehn, Douglas, Orth, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099203/
https://ncbi.nlm.nih.gov/pubmed/29682858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.24191
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