Natural biological variation of white matter microstructure is accentuated in Huntington's disease

Huntington's disease (HD) is a monogenic neurodegenerative disorder caused by a CAG‐repeat expansion in the Huntingtin gene. Presence of this expansion signifies certainty of disease onset, but only partly explains age at which onset occurs. Genome‐wide association studies have shown that natur...

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Publicat a:Hum Brain Mapp
Autors principals: Gregory, Sarah, Crawford, Helen, Seunarine, Kiran, Leavitt, Blair, Durr, Alexandra, Roos, Raymund A. C., Scahill, Rachael I., Tabrizi, Sarah J., Rees, Geraint, Langbehn, Douglas, Orth, Michael
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099203/
https://ncbi.nlm.nih.gov/pubmed/29682858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.24191
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