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Brain Regions Showing White Matter Loss in Huntington’s Disease Are Enriched for Synaptic and Metabolic Genes

BACKGROUND: The earliest white matter changes in Huntington’s disease are seen before disease onset in the premanifest stage around the striatum, within the corpus callosum, and in posterior white matter tracts. While experimental evidence suggests that these changes may be related to abnormal gene...

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Detaylı Bibliyografya
Yayımlandı:Biol Psychiatry
Asıl Yazarlar: McColgan, Peter, Gregory, Sarah, Seunarine, Kiran K., Razi, Adeel, Papoutsi, Marina, Johnson, Eileanoir, Durr, Alexandra, Roos, Raymund A.C., Leavitt, Blair R., Holmans, Peter, Scahill, Rachael I., Clark, Chris A., Rees, Geraint, Tabrizi, Sarah J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803509/
https://ncbi.nlm.nih.gov/pubmed/29174593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.10.019
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