Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington’s disease

Huntington’s disease can be predicted many years before symptom onset, and thus makes an ideal model for studying the earliest mechanisms of neurodegeneration. Diffuse patterns of structural connectivity loss occur in the basal ganglia and cortex early in the disease. However, the organizational pri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Brain
Auteurs principaux: McColgan, Peter, Seunarine, Kiran K., Razi, Adeel, Cole, James H., Gregory, Sarah, Durr, Alexandra, Roos, Raymund A. C., Stout, Julie C., Landwehrmeyer, Bernhard, Scahill, Rachael I., Clark, Chris A., Rees, Geraint, Tabrizi, Sarah J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620513/
https://ncbi.nlm.nih.gov/pubmed/26384928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv259
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