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Natural variation in sensory‐motor white matter organization influences manifestations of Huntington's disease

While the HTT CAG‐repeat expansion mutation causing Huntington's disease (HD) is highly correlated with the rate of pathogenesis leading to disease onset, considerable variance in age‐at‐onset remains unexplained. Therefore, other factors must influence the pathogenic process. We asked whether...

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Bibliographic Details
Published in:Hum Brain Mapp
Main Authors: Orth, Michael, Gregory, Sarah, Scahill, Rachael I, Mayer, Isabella SM, Minkova, Lora, Klöppel, Stefan, Seunarine, Kiran K, Boyd, Lara, Borowsky, Beth, Reilmann, Ralf, Bernhard Landwehrmeyer, G., Leavitt, Blair R, Roos, Raymund AC, Durr, Alexandra, Rees, Geraint, Rothwell, John C, Langbehn, Douglas, Tabrizi, Sarah J
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867476/
https://ncbi.nlm.nih.gov/pubmed/27477323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23332
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