Neurofilament light protein in blood predicts regional atrophy in Huntington disease

OBJECTIVE: Neurofilament light (NfL) protein in blood plasma has been proposed as a prognostic biomarker of neurodegeneration in a number of conditions, including Huntington disease (HD). This study investigates the regional distribution of NfL-associated neural pathology in HD gene expansion carrie...

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Pubblicato in:Neurology
Autori principali: Johnson, Eileanoir B., Byrne, Lauren M., Gregory, Sarah, Rodrigues, Filipe B., Blennow, Kaj, Durr, Alexandra, Leavitt, Blair R., Roos, Raymund A., Zetterberg, Henrik, Tabrizi, Sarah J., Scahill, Rachael I., Wild, Edward J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818166/
https://ncbi.nlm.nih.gov/pubmed/29367444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005005
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