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Neurofilament light protein in blood predicts regional atrophy in Huntington disease

OBJECTIVE: Neurofilament light (NfL) protein in blood plasma has been proposed as a prognostic biomarker of neurodegeneration in a number of conditions, including Huntington disease (HD). This study investigates the regional distribution of NfL-associated neural pathology in HD gene expansion carrie...

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Vydáno v:Neurology
Hlavní autoři: Johnson, Eileanoir B., Byrne, Lauren M., Gregory, Sarah, Rodrigues, Filipe B., Blennow, Kaj, Durr, Alexandra, Leavitt, Blair R., Roos, Raymund A., Zetterberg, Henrik, Tabrizi, Sarah J., Scahill, Rachael I., Wild, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818166/
https://ncbi.nlm.nih.gov/pubmed/29367444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005005
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