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Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S
At the heart of protein ubiquitination cascades, ubiquitin-conjugating enzymes (E2s) form reactive ubiquitin-thioester intermediates to enable efficient transfer of ubiquitin to cellular substrates. The precise regulation of E2s is thus crucial for cellular homeostasis and their deregulation is freq...
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| Udgivet i: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613103/ https://ncbi.nlm.nih.gov/pubmed/33082289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aba8208 |
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