Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains

Cellular adaptation to proteotoxic stress at the endoplasmic reticulum (ER) depends on Lys48-linked polyubiquitination by ER-associated ubiquitin ligases (E3s) and subsequent elimination of ubiquitinated retrotranslocation products by the proteasome. The ER-associated E3 gp78 ubiquitinates misfolded...

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Bibliografiske detaljer
Main Authors: Liu, Weixiao, Shang, Yongliang, Zeng, Yan, Liu, Chao, Li, Yanchang, Zhai, Linhui, Wang, Pan, Lou, Jizhong, Xu, Ping, Ye, Yihong, Li, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990682/
https://ncbi.nlm.nih.gov/pubmed/24366945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201385315
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