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Physics-driven coarse-grained model for biomolecular phase separation with near-quantitative accuracy

Various physics- and data-driven sequence-dependent protein coarse-grained models have been developed to study biomolecular phase separation and elucidate the dominant physicochemical driving forces. Here, we present Mpipi, a multiscale coarse-grained model that describes almost quantitatively the c...

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Veröffentlicht in:Nat Comput Sci
Hauptverfasser: Joseph, Jerelle A., Reinhardt, Aleks, Aguirre, Anne, Chew, Pin Yu, Russell, Kieran O., Espinosa, Jorge R., Garaizar, Adiran, Collepardo-Guevara, Rosana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612994/
https://ncbi.nlm.nih.gov/pubmed/35795820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43588-021-00155-3
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