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PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency
The Polycomb repressive system plays a fundamental role in controlling gene expression during mammalian development. To achieve this, Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) bind target genes and use histone modification-dependent feedback mechanisms to form Polycomb chromatin domains...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612713/ https://ncbi.nlm.nih.gov/pubmed/34608337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00661-y |
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