T cells armed with the C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours

The efficacy of adoptive cell therapy for solid tumours is hampered by the poor accumulation of the transferred T cells in tumour tissue. Here, we show that the forced expression of the C-X-C chemokine receptor type 6 (CXCR6, whose ligand is highly expressed by human and murine pancreatic cancer cel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Biomed Eng
Main Authors: Lesch, Stefanie, Blumenberg, Viktoria, Stoiber, Stefan, Gottschlich, Adrian, Ogonek, Justyna, Cadilha, Bruno L., Dantes, Zahra, Rataj, Felicitas, Dorman, Klara, Lutz, Johannes, Karches, Clara H., Heise, Constanze, Kurzay, Mathias, Larimer, Benjamin M., Grassmann, Simon, Rapp, Moritz, Nottebrock, Alessia, Kruger, Stephan, Tokarew, Nicholas, Metzger, Philipp, Hoerth, Christine, Benmebarek, Mohamed-Reda, Dhoqina, Dario, Grünmeier, Ruth, Seifert, Matthias, Oener, Arman, Umut, Öykü, Joaquina, Sandy, Vimeux, Lene, Tran, Thi, Hank, Thomas, Baba, Taisuke, Huynh, Duc, Megens, Remco TA., Janssen, Klaus-Peter, Jastroch, Martin, Lamp, Daniel, Ruehland, Svenja, Di Pilato, Mauro, Pruessmann, Jasper N., Thomas, Moritz, Marr, Carsten, Ormanns, Steffen, Reischer, Anna, Hristov, Michael, Tartour, Eric, Donnadieu, Emmanuel, Rothenfusser, Simon, Duewell, Peter, König, Lars M., Schnurr, Max, Subklewe, Marion, Liss, Andrew S., Halama, Niels, Reichert, Maximilian, Mempel, Thorsten R., Endres, Stefan, Kobold, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611996/
https://ncbi.nlm.nih.gov/pubmed/34083764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-021-00737-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados