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Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

Effective adoptive T cell therapy (ACT) comprises the killing of cancer cells through the therapeutic use of transferred T cells. One of the main ACT approaches is chimeric antigen receptor (CAR) T cell therapy. CAR T cells mediate MHC-unrestricted tumor cell killing by enabling T cells to bind targ...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Benmebarek, Mohamed-Reda, Karches, Clara Helke, Cadilha, Bruno Loureiro, Lesch, Stefanie, Endres, Stefan, Kobold, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470706/
https://ncbi.nlm.nih.gov/pubmed/30875739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061283
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