Structure-based Classification of Tauopathies

Ordered assembly of tau protein into filaments characterizes multiple neurodegenerative diseases, which are called tauopathies. We previously reported that by electron cryo-microscopy (cryo-EM), tau filament structures from Alzheimer’s disease (1,2), Pick’s disease (3), chronic traumatic encephalopa...

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Published in:Nature
Main Authors: Shi, Yang, Zhang, Wenjuan, Yang, Yang, Murzin, Alexey G., Falcon, Benjamin, Kotecha, Abhay, van Beers, Mike, Tarutani, Airi, Kametani, Fuyuki, Garringer, Holly J., Vidal, Ruben, Hallinan, Grace I., Lashley, Tammaryn, Saito, Yuko, Murayama, Shigeo, Yoshida, Mari, Tanaka, Hidetomo, Kakita, Akiyoshi, Ikeuchi, Takeshi, Robinson, Andrew C., Mann, David M.A., Kovacs, Gabor G., Revesz, Tamas, Ghetti, Bernardino, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H.W.
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611841/
https://ncbi.nlm.nih.gov/pubmed/34588692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03911-7
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