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Sense Codon Reassignment Enables Viral Resistance and Encoded Polymer Synthesis

It is widely hypothesized that removing cellular transfer RNAs (tRNAs) – making their cognate codons unreadable – might create a genetic firewall to viral infection and enable sense codon reassignment. However, it has been impossible to test these hypotheses. In this work, following synonymous codon...

詳細記述

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書誌詳細
出版年:Science
主要な著者: Robertson, Wesley E., Funke, Louise F. H., de la Torre, Daniel, Fredens, Julius, Elliott, Thomas S., Spinck, Martin, Christova, Yonka, Cervettini, Daniele, Böge, Franz L., Liu, Kim C., Buse, Salvador, Maslen, Sarah, Salmond, George P. C., Chin, Jason W.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611380/
https://ncbi.nlm.nih.gov/pubmed/34083482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg3029
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