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Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes

Nature regulates interference between cellular processes—allowing more complexity of life—by confining specific functions to organelles. Inspired by this concept, we designed an artificial organelle dedicated to protein engineering. We generated a membraneless organelle to translate only one type of...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Reinkemeier, Christopher D., Girona, Gemma Estrada, Lemke, Edward A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611745/
https://ncbi.nlm.nih.gov/pubmed/30923194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw2644
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