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Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes

Nature regulates interference between cellular processes—allowing more complexity of life—by confining specific functions to organelles. Inspired by this concept, we designed an artificial organelle dedicated to protein engineering. We generated a membraneless organelle to translate only one type of...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Reinkemeier, Christopher D., Girona, Gemma Estrada, Lemke, Edward A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611745/
https://ncbi.nlm.nih.gov/pubmed/30923194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw2644
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