Sense Codon Reassignment Enables Viral Resistance and Encoded Polymer Synthesis

It is widely hypothesized that removing cellular transfer RNAs (tRNAs) – making their cognate codons unreadable – might create a genetic firewall to viral infection and enable sense codon reassignment. However, it has been impossible to test these hypotheses. In this work, following synonymous codon...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Robertson, Wesley E., Funke, Louise F. H., de la Torre, Daniel, Fredens, Julius, Elliott, Thomas S., Spinck, Martin, Christova, Yonka, Cervettini, Daniele, Böge, Franz L., Liu, Kim C., Buse, Salvador, Maslen, Sarah, Salmond, George P. C., Chin, Jason W.
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611380/
https://ncbi.nlm.nih.gov/pubmed/34083482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg3029
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