Sense Codon Reassignment Enables Viral Resistance and Encoded Polymer Synthesis

It is widely hypothesized that removing cellular transfer RNAs (tRNAs) – making their cognate codons unreadable – might create a genetic firewall to viral infection and enable sense codon reassignment. However, it has been impossible to test these hypotheses. In this work, following synonymous codon...

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Publicado no:Science
Main Authors: Robertson, Wesley E., Funke, Louise F. H., de la Torre, Daniel, Fredens, Julius, Elliott, Thomas S., Spinck, Martin, Christova, Yonka, Cervettini, Daniele, Böge, Franz L., Liu, Kim C., Buse, Salvador, Maslen, Sarah, Salmond, George P. C., Chin, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611380/
https://ncbi.nlm.nih.gov/pubmed/34083482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg3029
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