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Glypicans shield the Wnt lipid moiety to enable signalling at a distance

A relatively small number of proteins have been suggested to act as morphogens, signalling molecules that spread within tissues to organize cell fate specification during development and tissue repair. Among them are Wnt proteins, which carry a palmitoleate moiety that is essential for signalling ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: McGough, Ian J., Vecchia, Luca, Bishop, Benjamin, Malinauskas, Tomas, Beckett, Karen, Joshi, Dhira, O'Reilly, Nicola, Siebold, Christian, Jones, E. Yvonne, Vincent, Jean-Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610841/
https://ncbi.nlm.nih.gov/pubmed/32699409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2498-z
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