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p62 -mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy
The degradation of misfolded proteins is essential for cellular homeostasis. Misfolded proteins are normally degraded by the ubiquitin-proteasome system (UPS), and selective autophagy serves as backup mechanisms when the UPS is overloaded. Selective autophagy mediates the degradation of harmful mate...
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| Pubblicato in: | J Cell Sci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610772/ https://ncbi.nlm.nih.gov/pubmed/30287680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.214304 |
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