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p62 -mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy

The degradation of misfolded proteins is essential for cellular homeostasis. Misfolded proteins are normally degraded by the ubiquitin-proteasome system (UPS), and selective autophagy serves as backup mechanisms when the UPS is overloaded. Selective autophagy mediates the degradation of harmful mate...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Cell Sci
Päätekijät: Danieli, Alberto, Martens, Sascha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610772/
https://ncbi.nlm.nih.gov/pubmed/30287680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.214304
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