Φορτώνει......
Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
Targeted gene editing in hematopoietic stem cells (HSCs) is a promising treatment for several diseases. However, the limited efficiency of homology-directed repair (HDR) in HSCs and the unknown impact of the procedure on clonal composition and dynamics upon transplantation have hampered clinical tra...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Biotechnol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610558/ https://ncbi.nlm.nih.gov/pubmed/32601433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0551-y |
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