Cholangiocyte organoids can repair bile ducts after transplantation in human liver

Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. Here, we address this challenge in the context of cholangiocyte organoids and cholangiopathies, which represent a leading indication for liver transplantation. Using single-cell RNA sequencing w...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C., Sawiak, Stephen, Beach, Timothy E., Godfrey, Edmund M., Upponi, Sara S., Brevini, Teresa, Wesley, Brandon T., Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, Richard, Berntsen, Natalie L., Mulcahy, Victoria L., Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E., Osnato, Anna, Murphy, Michael P., Corbett, Gareth, Gelson, William T. H., Mells, George F., Humphreys, Peter, Davies, Susan E., Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A., Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J. E., Saeb-Parsy, Kourosh, Vallier, Ludovic
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610478/
https://ncbi.nlm.nih.gov/pubmed/33602855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6964
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