Cholangiocyte organoids can repair bile ducts after transplantation in human liver

Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. Here, we address this challenge in the context of cholangiocyte organoids and cholangiopathies, which represent a leading indication for liver transplantation. Using single-cell RNA sequencing w...

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מידע ביבליוגרפי
הוצא לאור ב:Science
Main Authors: Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C., Sawiak, Stephen, Beach, Timothy E., Godfrey, Edmund M., Upponi, Sara S., Brevini, Teresa, Wesley, Brandon T., Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, Richard, Berntsen, Natalie L., Mulcahy, Victoria L., Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E., Osnato, Anna, Murphy, Michael P., Corbett, Gareth, Gelson, William T. H., Mells, George F., Humphreys, Peter, Davies, Susan E., Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A., Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J. E., Saeb-Parsy, Kourosh, Vallier, Ludovic
פורמט: Artigo
שפה:Inglês
יצא לאור: 2021
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610478/
https://ncbi.nlm.nih.gov/pubmed/33602855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6964
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