Cholangiocyte organoids can repair bile ducts after transplantation in human liver

Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. Here, we address this challenge in the context of cholangiocyte organoids and cholangiopathies, which represent a leading indication for liver transplantation. Using single-cell RNA sequencing w...

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Библиографические подробности
Опубликовано в: :Science
Главные авторы: Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C., Sawiak, Stephen, Beach, Timothy E., Godfrey, Edmund M., Upponi, Sara S., Brevini, Teresa, Wesley, Brandon T., Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, Richard, Berntsen, Natalie L., Mulcahy, Victoria L., Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E., Osnato, Anna, Murphy, Michael P., Corbett, Gareth, Gelson, William T. H., Mells, George F., Humphreys, Peter, Davies, Susan E., Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A., Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J. E., Saeb-Parsy, Kourosh, Vallier, Ludovic
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610478/
https://ncbi.nlm.nih.gov/pubmed/33602855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6964
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