Cholangiocyte organoids can repair bile ducts after transplantation in human liver

Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. Here, we address this challenge in the context of cholangiocyte organoids and cholangiopathies, which represent a leading indication for liver transplantation. Using single-cell RNA sequencing w...

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Publicado no:Science
Main Authors: Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C., Sawiak, Stephen, Beach, Timothy E., Godfrey, Edmund M., Upponi, Sara S., Brevini, Teresa, Wesley, Brandon T., Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, Richard, Berntsen, Natalie L., Mulcahy, Victoria L., Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E., Osnato, Anna, Murphy, Michael P., Corbett, Gareth, Gelson, William T. H., Mells, George F., Humphreys, Peter, Davies, Susan E., Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A., Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J. E., Saeb-Parsy, Kourosh, Vallier, Ludovic
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610478/
https://ncbi.nlm.nih.gov/pubmed/33602855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6964
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