Cholangiocyte organoids can repair bile ducts after transplantation in human liver

Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. Here, we address this challenge in the context of cholangiocyte organoids and cholangiopathies, which represent a leading indication for liver transplantation. Using single-cell RNA sequencing w...

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Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C., Sawiak, Stephen, Beach, Timothy E., Godfrey, Edmund M., Upponi, Sara S., Brevini, Teresa, Wesley, Brandon T., Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, Richard, Berntsen, Natalie L., Mulcahy, Victoria L., Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E., Osnato, Anna, Murphy, Michael P., Corbett, Gareth, Gelson, William T. H., Mells, George F., Humphreys, Peter, Davies, Susan E., Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A., Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J. E., Saeb-Parsy, Kourosh, Vallier, Ludovic
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610478/
https://ncbi.nlm.nih.gov/pubmed/33602855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6964
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