Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome

OBJECTIVES: Humanised mice have emerged as valuable models for pre‐clinical testing of the safety and efficacy of immunotherapies. Given the variety of models available, selection of the most appropriate humanised mouse model is critical in study design. Here, we aimed to develop a model for predict...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Matas‐Céspedes, Alba, Brown, Lee, Mahbubani, Krishnaa T, Bareham, Bethany, Higgins, Jackie, Curran, Michelle, de Haan, Lolke, Lapointe, Jean‐Martin, Stebbings, Richard, Saeb‐Parsy, Kourosh
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641894/
https://ncbi.nlm.nih.gov/pubmed/33173582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1202
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