Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome

OBJECTIVES: Humanised mice have emerged as valuable models for pre‐clinical testing of the safety and efficacy of immunotherapies. Given the variety of models available, selection of the most appropriate humanised mouse model is critical in study design. Here, we aimed to develop a model for predict...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Matas‐Céspedes, Alba, Brown, Lee, Mahbubani, Krishnaa T, Bareham, Bethany, Higgins, Jackie, Curran, Michelle, de Haan, Lolke, Lapointe, Jean‐Martin, Stebbings, Richard, Saeb‐Parsy, Kourosh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641894/
https://ncbi.nlm.nih.gov/pubmed/33173582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1202
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