Tumor‐like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin‐induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat

AIMS/INTRODUCTION: Pancreatic islets are heterogenous. To clarify the relationship between islet heterogeneity and incretin action in the islets, we studied gene expression and metabolic profiles of non‐large and enlarged islets of the Zucker fatty diabetes mellitus rat, an obese diabetes model, as...

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Pubblicato in:J Diabetes Investig
Autori principali: Hayami, Tomohide, Yokoi, Norihide, Yamaguchi, Takuro, Honda, Kohei, Murao, Naoya, Takahashi, Harumi, Wang, Shujie, Seino, Yusuke, Kamiya, Hideki, Yabe, Daisuke, Sweet, Ian R, Mizoguchi, Akira, Nakamura, Jiro, Seino, Susumu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610108/
https://ncbi.nlm.nih.gov/pubmed/32279428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13272
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