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Demystifying the catalytic pathway of Mycobacterium tuberculosis isocitrate lyase

Pulmonary tuberculosis, caused by Mycobacterium tuberculosis, is one of the most persistent diseases leading to death in humans. As one of the key targets during the latent/dormant stage of M. tuberculosis, isocitrate lyase (ICL) has been a subject of interest for new tuberculosis therapeutics. In t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ibeji, Collins U., Salleh, Nor Amirah Mohd, Sum, Jia Siang, Ch’ng, Angela Chiew Wen, Lim, Theam Soon, Choong, Yee Siew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609661/
https://ncbi.nlm.nih.gov/pubmed/33144641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75799-8
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