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Cognizance of Molecular Methods for the Generation of Mutagenic Phage Display Antibody Libraries for Affinity Maturation

Antibodies leverage on their unique architecture to bind with an array of antigens. The strength of interaction has a direct relation to the affinity of the antibodies towards the antigen. In vivo affinity maturation is performed through multiple rounds of somatic hypermutation and selection in the...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Lim, Chia Chiu, Choong, Yee Siew, Lim, Theam Soon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515083/
https://ncbi.nlm.nih.gov/pubmed/30991723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081861
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