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Cognizance of Molecular Methods for the Generation of Mutagenic Phage Display Antibody Libraries for Affinity Maturation
Antibodies leverage on their unique architecture to bind with an array of antigens. The strength of interaction has a direct relation to the affinity of the antibodies towards the antigen. <i>In vivo</i> affinity maturation is performed through multiple rounds of somatic hypermutation an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2019-04-01
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| Colecção: | International Journal of Molecular Sciences |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1422-0067/20/8/1861 |
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