Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate

The Nrf2 transcription factor is a key regulator of redox reactions and considered the main target for the multiple sclerosis (MS) drug dimethyl fumarate (DMF). However, exploration of additional Nrf2-activating compounds is motivated, since DMF displays significant off-target effects and has a rela...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurotherapeutics
Prif Awduron: Carlström, Karl E., Chinthakindi, Praveen K., Espinosa, Belén, Al Nimer, Faiez, Arnér, Elias S. J., Arvidsson, Per I., Piehl, Fredrik, Johansson, Katarina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609514/
https://ncbi.nlm.nih.gov/pubmed/32394330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00855-0
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg