Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution

Aim: Many transcription factors with importance in health and disease are redox regulated. However, how their activities may be intertwined in responses to redox-perturbing stimuli is poorly understood. To enable in-depth characterization of this aspect, we here developed a methodology for simultane...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Johansson, Katarina, Cebula, Marcus, Rengby, Olle, Dreij, Kristian, Carlström, Karl E., Sigmundsson, Kristmundur, Piehl, Fredrik, Arnér, Elias S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Forum Original Research CommunicationsRedox Therapeutics (K.D. Tew, Ed.)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704776/
https://ncbi.nlm.nih.gov/pubmed/26415122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6419
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