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LocusFocus: Web-based colocalization for the annotation and functional follow-up of GWAS

Genome-wide association studies (GWAS) have primarily identified trait-associated loci in the non-coding genome. Colocalization analyses of SNP associations from GWAS with expression quantitative trait loci (eQTL) evidence enable the generation of hypotheses about responsible mechanism, genes and ti...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Panjwani, Naim, Wang, Fan, Mastromatteo, Scott, Bao, Allen, Wang, Cheng, He, Gengming, Gong, Jiafen, Rommens, Johanna M., Sun, Lei, Strug, Lisa J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608978/
https://ncbi.nlm.nih.gov/pubmed/33090994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008336
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