Mechanisms Regulating Muscle Protein Synthesis in CKD

BACKGROUND: CKD induces loss of muscle proteins partly by suppressing muscle protein synthesis. Muscles of mice with CKD have increased expression of nucleolar protein 66 (NO66), as do muscle biopsy specimens from patients with CKD or those undergoing hemodialysis. Inflammation stimulates NO66 expre...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Zhang, Liping, Chen, Qin, Chen, Zihong, Wang, Ying, Gamboa, Jorge L., Ikizler, Talat Alp, Garibotto, Giacomo, Mitch, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2020
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608956/
https://ncbi.nlm.nih.gov/pubmed/32764136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019121277
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