Mechanisms Regulating Muscle Protein Synthesis in CKD

BACKGROUND: CKD induces loss of muscle proteins partly by suppressing muscle protein synthesis. Muscles of mice with CKD have increased expression of nucleolar protein 66 (NO66), as do muscle biopsy specimens from patients with CKD or those undergoing hemodialysis. Inflammation stimulates NO66 expre...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Zhang, Liping, Chen, Qin, Chen, Zihong, Wang, Ying, Gamboa, Jorge L., Ikizler, Talat Alp, Garibotto, Giacomo, Mitch, William E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2020
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608956/
https://ncbi.nlm.nih.gov/pubmed/32764136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019121277
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