Mechanisms Regulating Muscle Protein Synthesis in CKD

BACKGROUND: CKD induces loss of muscle proteins partly by suppressing muscle protein synthesis. Muscles of mice with CKD have increased expression of nucleolar protein 66 (NO66), as do muscle biopsy specimens from patients with CKD or those undergoing hemodialysis. Inflammation stimulates NO66 expre...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Zhang, Liping, Chen, Qin, Chen, Zihong, Wang, Ying, Gamboa, Jorge L., Ikizler, Talat Alp, Garibotto, Giacomo, Mitch, William E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2020
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608956/
https://ncbi.nlm.nih.gov/pubmed/32764136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019121277
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