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Skeletal Muscle Mitochondrial Dysfunction Is Present in Patients with CKD before Initiation of Maintenance Hemodialysis

BACKGROUND AND OBJECTIVES: Patients with CKD suffer from frailty and sarcopenia, which is associated with higher morbidity and mortality. Skeletal muscle mitochondria are important for physical function and could be a target to prevent frailty and sarcopenia. In this study, we tested the hypothesis...

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Опубликовано в: :Clin J Am Soc Nephrol
Главные авторы: Gamboa, Jorge L., Roshanravan, Baback, Towse, Theodore, Keller, Chad A., Falck, Aaron M., Yu, Chang, Frontera, Walter R., Brown, Nancy J., Ikizler, T. Alp
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341789/
https://ncbi.nlm.nih.gov/pubmed/32591419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.10320819
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